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Oudere vrouw met bril leest papieren aan een houten tafel, met een boekenkast op de achtergrond

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Afvallen

Dit werkboek is gebaseerd op 11 bronnen. Naar het werkboek

  1. Franz MJ, VanWormer JJ, Crain AL, et al. Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up. J Am Diet Assoc. 2007;107(10):1755-67. doi:10.1016/j.jada.2007.07.017
  2. Tobias DK, Chen M, Manson JE, et al. Effect of low-fat diet interventions versus other diet interventions on long-term weight change in adults: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2015;3(12):968-79. doi:10.1016/S2213-8587(15)00367-8
  3. Lei L, Huang J, Zhang L, et al. Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors in overweight and obese adults: a meta-analysis of randomized controlled trials. Front Nutr. 2022;9:935234. doi:10.3389/fnut.2022.935234
  4. Hall KD, Guo J. Obesity energetics: body weight regulation and the effects of diet composition. Gastroenterology. 2017;152(7):1718-27.e3. doi:10.1053/j.gastro.2017.01.052
  5. Thorogood A, Mottillo S, Shimony A, et al. Isolated aerobic exercise and weight loss: a systematic review and meta-analysis of randomized controlled trials. Am J Med. 2011;124(8):747-55. doi:10.1016/j.amjmed.2011.02.037
  6. Leidy HJ, Clifton PM, Astrup A, et al. The role of protein in weight loss and maintenance. Am J Clin Nutr. 2015;101(6):1320S-9S. doi:10.3945/ajcn.114.084038
  7. Te Morenga L, Mallard S, Mann J. Dietary sugars and body weight: systematic review and meta-analyses of randomised controlled trials and cohort studies. BMJ. 2012;346:e7492. doi:10.1136/bmj.e7492
  8. Patikorn C, Roubal K, Veettil SK, et al. Intermittent fasting and obesity-related health outcomes: an umbrella review of meta-analyses of randomized clinical trials. JAMA Netw Open. 2021;4(12):e2139558. doi:10.1001/jamanetworkopen.2021.39558
  9. Chaput JP, McHill AW, Cox RC, et al. The role of insufficient sleep and circadian misalignment in obesity. Nat Rev Endocrinol. 2023;19(2):82-97. doi:10.1038/s41574-022-00747-7
  10. Hill D, Conner M, Clancy F, et al. Stress and eating behaviours in healthy adults: a systematic review and meta-analysis. Health Psychol Rev. 2022;16(2):280-304. doi:10.1080/17437199.2021.1923406
  11. Rabbani N, Thornalley PJ. Unraveling the impaired incretin effect in obesity and type 2 diabetes: key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload. Diabetes Res Clin Pract. 2024;217:111905. doi:10.1016/j.diabres.2024.111905

Alzheimer en dementie

Dit werkboek is gebaseerd op 11 bronnen. Naar het werkboek

  1. Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet. 2024;404(10452):572-628. doi:10.1016/S0140-6736(24)01296-0
  2. Scheltens P, De Strooper B, Kivipelto M, et al. Alzheimer's disease. Lancet. 2021;397(10284):1577-90. doi:10.1016/S0140-6736(20)32205-4
  3. Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis. JAMA. 1997;278(16):1349-56. doi:10.1001/jama.1997.03550160069041
  4. Hörder H, Johansson L, Guo X, et al. Midlife cardiovascular fitness and dementia: a 44-year longitudinal population study in women. Neurology. 2018;90(15):e1298-305. doi:10.1212/WNL.0000000000005290
  5. Ngandu T, Lehtisalo J, Solomon A, et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet. 2015;385(9984):2255-63. doi:10.1016/S0140-6736(15)60461-5
  6. Chatterjee S, Peters SAE, Woodward M, et al. Type 2 diabetes as a risk factor for dementia in women compared with men: a pooled analysis of 2.3 million people comprising more than 100,000 cases of dementia. Diabetes Care. 2016;39(2):300-7. doi:10.2337/dc15-1588
  7. Zhong G, Wang Y, Zhang Y, et al. Smoking is associated with an increased risk of dementia: a meta-analysis of prospective cohort studies with investigation of potential effect modifiers. PLoS One. 2015;10(3):e0118333. doi:10.1371/journal.pone.0118333
  8. Li H, Li S, Yang H, et al. Association of ultraprocessed food consumption with risk of dementia: a prospective cohort study. Neurology. 2022;99(10):e1056-66. doi:10.1212/WNL.0000000000200871
  9. Wu L, Sun D. Adherence to Mediterranean diet and risk of developing cognitive disorders: an updated systematic review and meta-analysis of prospective cohort studies. Sci Rep. 2017;7:41317. doi:10.1038/srep41317
  10. Iso-Markku P, Kujala UM, Knittle K, et al. Physical activity as a protective factor for dementia and Alzheimer's disease: systematic review, meta-analysis and quality assessment of cohort and case-control studies. Br J Sports Med. 2022;56(12):701-9. doi:10.1136/bjsports-2021-104981
  11. Bubu OM, Brannick M, Mortimer J, et al. Sleep, cognitive impairment, and Alzheimer's disease: a systematic review and meta-analysis. Sleep. 2017;40(1):zsw032. doi:10.1093/sleep/zsw032

Artrose

Dit werkboek is gebaseerd op 5 bronnen. Naar het werkboek

  1. Weng Q, Goh SL, Wu J, et al. Comparative efficacy of exercise therapy and oral non-steroidal anti-inflammatory drugs and paracetamol for knee or hip osteoarthritis: a network meta-analysis of randomised controlled trials. Br J Sports Med. 2023;57(15):990-6. doi:10.1136/bjsports-2022-105898
  2. Messier SP, Gutekunst DJ, Davis C, et al. Weight loss reduces knee-joint loads in overweight and obese older adults with knee osteoarthritis. Arthritis Rheum. 2005;52(7):2026-32. doi:10.1002/art.21139
  3. Walrabenstein W, Wagenaar CA, van de Put M, et al. A multidisciplinary lifestyle program for metabolic syndrome-associated osteoarthritis: the "Plants for Joints" randomized controlled trial. Osteoarthritis Cartilage. 2023;31(11):1491-500. doi:10.1016/j.joca.2023.05.014
  4. Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 ACR/Arthritis Foundation Guideline for the Management of Osteoarthritis. Arthritis Care Res. 2020;72:149-162. doi:10.1002/acr.24131
  5. NICE. Osteoarthritis in over 16s: diagnosis and management. Guideline NG226. 2022.

Beginnende dementie

Dit werkboek is gebaseerd op 10 bronnen. Naar het werkboek

  1. Ornish D, Madison C, Kivipelto M, et al. Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer's disease: a randomized, controlled clinical trial. Alzheimers Res Ther. 2024;16(1):122. doi:10.1186/s13195-024-01482-z
  2. Bingham EM, Hopkins D, Smith D, et al. The role of insulin in human brain glucose metabolism: an 18fluoro-deoxyglucose positron emission tomography study. Diabetes. 2002;51(12):3384-90. doi:10.2337/diabetes.51.12.3384
  3. Feng F, Xu H, Sun Y, et al. Exercise for prevention of falls and fall-related injuries in neurodegenerative diseases and aging-related risk conditions: a meta-analysis. Front Endocrinol (Lausanne). 2023;14:1187325. doi:10.3389/fendo.2023.1187325
  4. Sun G, Ding X, Ma H, et al. Impact of exercise intervention on depression, anxiety, sleep and quality of life in patients with cognitive impairment: a systematic review and network meta-analysis. Front Psychiatry. 2025;16:1666157. doi:10.3389/fpsyt.2025.1666157
  5. Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342(6156):373-7. doi:10.1126/science.1241224
  6. Hauglund NL, Andersen M, Tokarska K, et al. Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep. Cell. 2025;188(3):606-622.e17. doi:10.1016/j.cell.2024.11.027
  7. Woods B, Rai HK, Elliott E, et al. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev. 2023;1(1):CD005562. doi:10.1002/14651858.CD005562.pub3
  8. Volkert D, Beck AM, Faxén-Irving G, et al. ESPEN guideline on nutrition and hydration in dementia - Update 2024. Clin Nutr. 2024;43(6):1599-626. doi:10.1016/j.clnu.2024.04.039
  9. NICE. Delirium: prevention, diagnosis and management in hospital and long-term care. CG103, aanbeveling 1.3.1; bijgewerkt 2023.
  10. Eizenga WH, Dautzenberg PLJ, Eekhof JAH, et al. NHG-Standaard Delier (eerste herziening). Huisarts Wet. 2014;57(4):184-93. Kernboodschappen.

Beweging

Dit werkboek is gebaseerd op 11 bronnen. Naar het werkboek

  1. Ding D, Nguyen B, Nau T, et al. Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis. Lancet Public Health. 2025;10(8):e668-81. doi:10.1016/S2468-2667(25)00164-1
  2. Bull FC, Al-Ansari SS, Biddle S, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020;54(24):1451-62. doi:10.1136/bjsports-2020-102955
  3. Gezondheidsraad. Beweegrichtlijnen 2017. Den Haag: Gezondheidsraad; 2017. https://www.gezondheidsraad.nl/documenten/adviezen/2017/08/22/beweegrichtlijnen-2017
  4. Biswas A, Oh PI, Faulkner GE, et al. Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis. Ann Intern Med. 2015;162(2):123-32. doi:10.7326/M14-1651
  5. Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc. 2013;2(1):e004473. doi:10.1161/JAHA.112.004473
  6. Richter EA, Hargreaves M. Exercise, GLUT4, and skeletal muscle glucose uptake. Physiol Rev. 2013;93(3):993-1017. doi:10.1152/physrev.00038.2012
  7. Engeroff T, Groneberg DA, Wilke J. After dinner rest a while, after supper walk a mile? A systematic review with meta-analysis on the acute postprandial glycemic response to exercise before and after meal ingestion in healthy subjects and patients with impaired glucose tolerance. Sports Med. 2023;53(4):849-69. doi:10.1007/s40279-022-01808-7
  8. Sherrington C, Fairhall NJ, Wallbank GK, et al. Exercise for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2019;1(1):CD012424. doi:10.1002/14651858.CD012424.pub2
  9. Noetel M, Sanders T, Gallardo-Gómez D, et al. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. BMJ. 2024;384:e075847. doi:10.1136/bmj-2023-075847
  10. Lopez P, Taaffe DR, Galvão DA, et al. Resistance training effectiveness on body composition and body weight outcomes in individuals with overweight and obesity across the lifespan: a systematic review and meta-analysis. Obes Rev. 2022;23(5):e13428. doi:10.1111/obr.13428
  11. Wewege M, van den Berg R, Ward RE, Keech A. The effects of high-intensity interval training vs. moderate-intensity continuous training on body composition in overweight and obese adults: a systematic review and meta-analysis. Obes Rev. 2017;18(6):635-46. doi:10.1111/obr.12532

Depressie

Dit werkboek is gebaseerd op 9 bronnen. Naar het werkboek

  1. Noetel M, Sanders T, Gallardo-Gómez D, et al. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. BMJ. 2024;384:e075847. doi:10.1136/bmj-2023-075847
  2. Jacka FN, O'Neil A, Opie R, et al. A randomised controlled trial of dietary improvement for adults with major depression (the 'SMILES' trial). BMC Med. 2017;15(1):23. doi:10.1186/s12916-017-0791-y
  3. Stetler C, Miller GE. Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research. Psychosom Med. 2011;73(2):114-26. doi:10.1097/PSY.0b013e31820ad12b
  4. Francis HM, Stevenson RJ, Chambers JR, et al. A brief diet intervention can reduce symptoms of depression in young adults - A randomised controlled trial. PLoS One. 2019;14(10):e0222768. doi:10.1371/journal.pone.0222768
  5. Singh B, Murphy A, Maher C, et al. Time to Form a Habit: A Systematic Review and Meta-Analysis of Health Behaviour Habit Formation and Its Determinants. Healthcare (Basel). 2024;12(23). doi:10.3390/healthcare12232488
  6. Casacalenda N, Perry JC, Looper K. Remission in major depressive disorder: a comparison of pharmacotherapy, psychotherapy, and control conditions. Am J Psychiatry. 2002;159(8):1354-60. doi:10.1176/appi.ajp.159.8.1354
  7. Lewis G, Marston L, Duffy L, et al. Maintenance or Discontinuation of Antidepressants in Primary Care. N Engl J Med. 2021;385(14):1257-67. doi:10.1056/NEJMoa2106356
  8. Kan C, Silva N, Golden SH, et al. A systematic review and meta-analysis of the association between depression and insulin resistance. Diabetes Care. 2013;36(2):480-9. doi:10.2337/dc12-1442
  9. Watson KT, Simard JF, Henderson VW, et al. Incident major depressive disorder predicted by three measures of insulin resistance: a Dutch cohort study. Am J Psychiatry. 2021;178(10):914-20. doi:10.1176/appi.ajp.2021.20101479

Diabetes type 2

Dit werkboek is gebaseerd op 8 bronnen. Naar het werkboek

  1. Diabetes Fonds. Diabetes in cijfers. Amersfoort: Diabetes Fonds; 2024. https://www.diabetesfonds.nl/over-diabetes/diabetes-in-het-algemeen/diabetes-in-cijfers
  2. Riddle MC, Cefalu WT, Evans PH, et al. Consensus report: definition and interpretation of remission in type 2 diabetes. Diabetes Care. 2021;44(10):2438-44. doi:10.2337/dci21-0034
  3. Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet. 2018;391(10120):541-51. doi:10.1016/S0140-6736(17)33102-1
  4. Goldenberg JZ, Day A, Brinkworth GD, et al. Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data. BMJ. 2021;372:m4743. doi:10.1136/bmj.m4743
  5. Snorgaard O, Poulsen GM, Andersen HK, et al. Systematic review and meta-analysis of dietary carbohydrate restriction in patients with type 2 diabetes. BMJ Open Diabetes Res Care. 2017;5(1):e000354. doi:10.1136/bmjdrc-2016-000354
  6. Westman EC, Yancy WS, Mavropoulos JC, et al. The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus. Nutr Metab (Lond). 2008;5:36. doi:10.1186/1743-7075-5-36
  7. Engeroff T, Groneberg DA, Wilke J. After dinner rest a while, after supper walk a mile? A systematic review with meta-analysis on the acute postprandial glycemic response to exercise before and after meal ingestion in healthy subjects and patients with impaired glucose tolerance. Sports Med. 2023;53(4):849-69. doi:10.1007/s40279-022-01808-7
  8. Buxton OM, Pavlova M, Reid EW, et al. Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes. 2010;59(9):2126-33. doi:10.2337/db09-0699

Epilepsie

Dit werkboek is gebaseerd op 8 bronnen. Naar het werkboek

  1. Faught E, Duh MS, Weiner JR, et al. Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM Study. Neurology. 2008;71(20):1572-8. doi:10.1212/01.wnl.0000319693.10338.b9
  2. Lin Z, Si Q, Xiaoyi Z. Obstructive sleep apnoea in patients with epilepsy: a meta-analysis. Sleep Breath. 2017;21(2):263-70. doi:10.1007/s11325-016-1391-3
  3. Huang Y, Nevitt SJ, Mayer J, et al. Service delivery, behavioural, and self-management interventions for adults with epilepsy. Cochrane Database Syst Rev. 2025;9:CD015284. doi:10.1002/14651858.CD015284.pub2
  4. Johnson EC, Helen Cross J, Reilly C. Physical activity in people with epilepsy: A systematic review. Epilepsia. 2020;61(6):1062-81. doi:10.1111/epi.16517
  5. van Koert RR, Bauer PR, Schuitema I, et al. Caffeine and seizures: A systematic review and quantitative analysis. Epilepsy Behav. 2018;80:37-47. doi:10.1016/j.yebeh.2017.11.003
  6. Martin-McGill KJ, Bresnahan R, Levy RG, et al. Ketogenic diets for drug-resistant epilepsy. Cochrane Database Syst Rev. 2020;6(6):CD001903. doi:10.1002/14651858.CD001903.pub5
  7. Cervenka MC, Wood S, Bagary M, et al. International Recommendations for the Management of Adults Treated With Ketogenic Diet Therapies. Neurol Clin Pract. 2021;11(5):385-397. doi:10.1212/CPJ.0000000000001007
  8. Department of Health and Social Care. Clinical guidelines for alcohol treatment. 10. Pharmacological interventions. 2025. Geraadpleegd 7 oktober 2026.

Hart- en vaatziekten

Dit werkboek is gebaseerd op 7 bronnen. Naar het werkboek

  1. Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364(9438):937-52. doi:10.1016/S0140-6736(04)17018-9
  2. O'Donnell MJ, Chin SL, Rangarajan S, et al. Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study. Lancet. 2016;388(10046):761-75. doi:10.1016/S0140-6736(16)30506-2
  3. Estruch R, Ros E, Salas-Salvadó J, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N Engl J Med. 2018;378(25):e34. doi:10.1056/NEJMoa1800389
  4. World Health Organization. Tobacco: Health benefits of smoking cessation. 25 February 2020. Geraadpleegd 7 oktober 2026.
  5. Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120(16):1640-5. doi:10.1161/CIRCULATIONAHA.109.192644
  6. Edwards JJ, Deenmamode AHP, Griffiths M, et al. Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials. Br J Sports Med. 2023;57(20):1317-26. doi:10.1136/bjsports-2022-106503
  7. National Institute for Health and Care Excellence. Acute coronary syndromes. NICE guideline NG185, recommendations 1.4.13 and 1.8.1. 2020. Geraadpleegd 7 oktober 2026.

Hoge bloeddruk

Dit werkboek is gebaseerd op 25 bronnen. Naar het werkboek

  1. Hall JE, do Carmo JM, da Silva AA, Wang Z, Hall ME. Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms. Circ Res. 2015;116(6):991-1006. doi:10.1161/CIRCRESAHA.116.305697
  2. Hill MA, Yang Y, Zhang L, Sun Z, Jia G, Parrish AR, et al. Insulin resistance, cardiovascular stiffening and cardiovascular disease. Metabolism. 2021;119:154766. doi:10.1016/j.metabol.2021.154766
  3. Jia G, Sowers JR. Hypertension in diabetes: an update of basic mechanisms and clinical disease. Hypertension. 2021;78(5):1197-1205. doi:10.1161/HYPERTENSIONAHA.121.17981
  4. Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension. 2003;42(5):878-84. doi:10.1161/01.HYP.0000094221.86888.AE
  5. Chatzi CA, Basios A, Markozannes G, Ntzani EE, Tsilidis KK, Kazakos K, et al. Effect of different dietary patterns on cardiometabolic risk factors: an umbrella review of systematic reviews and meta-analyses. Nutrients. 2024;16(22):3873. doi:10.3390/nu16223873
  6. Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ. 2003;326(7404):1427. doi:10.1136/bmj.326.7404.1427
  7. Ettehad D, Emdin CA, Kiran A, Anderson SG, Callender T, Emberson J, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet. 2016;387(10022):957-67. doi:10.1016/S0140-6736(15)01225-8
  8. Filippini T, Naska A, Kasdagli MI, Torres D, Lopes C, Carvalho C, et al. Potassium intake and blood pressure: a dose-response meta-analysis of randomized controlled trials. J Am Heart Assoc. 2020;9(12):e015719. doi:10.1161/JAHA.119.015719
  9. Murdoch C, Unwin D, Cavan D, Cucuzzella M, Patel M. Adapting diabetes medication for low carbohydrate management of type 2 diabetes: a practical guide. Br J Gen Pract. 2019;69(684):360-1. doi:10.3399/bjgp19X704525
  10. Chaddha A, Modaff D, Hooper-Lane C, Feldstein DA. Device and non-device-guided slow breathing to reduce blood pressure: a systematic review and meta-analysis. Complement Ther Med. 2019;45:179-84. doi:10.1016/j.ctim.2019.03.005
  11. Satapathy P, Gaidhane AM, Vadia N, Menon SV, Chennakesavulu K, Panigrahi R, et al. Between depression and risk of hypertension: a systematic review and meta-analysis. Brain Behav. 2025;15(9):e70931. doi:10.1002/brb3.70931
  12. Pan Y, Cai W, Cheng Q, Dong W, An T, Yan J. Association between anxiety and hypertension: a systematic review and meta-analysis of epidemiological studies. Neuropsychiatr Dis Treat. 2015;11:1121-30. doi:10.2147/NDT.S77710
  13. Edwards JJ, Deenmamode AHP, Griffiths M, Arnold O, Cooper NJ, Wiles JD, et al. Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials. Br J Sports Med. 2023;57(20):1317-26. doi:10.1136/bjsports-2022-106503
  14. Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med. 2001;344(1):3-10. doi:10.1056/NEJM200101043440101
  15. Koenen M, Hill MA, Cohen P, Sowers JR. Obesity, adipose tissue and vascular dysfunction. Circ Res. 2021;128(7):951-68. doi:10.1161/CIRCRESAHA.121.318093
  16. Huang L, Trieu K, Yoshimura S, Neal B, Woodward M, Campbell NRC, et al. Effect of dose and duration of reduction in dietary sodium on blood pressure levels: systematic review and meta-analysis of randomised trials. BMJ. 2020;368:m315. doi:10.1136/bmj.m315
  17. Sun W, Han Y, Gu S. Effects of five types of exercise on vascular function in postmenopausal women: a network meta-analysis and systematic review of 32 randomized controlled trials. PeerJ. 2024;12:e17621. doi:10.7717/peerj.17621
  18. Monticone S, Burrello J, Tizzani D, Bertello C, Viola A, Buffolo F, et al. Prevalence and clinical manifestations of primary aldosteronism encountered in primary care practice. J Am Coll Cardiol. 2017;69(14):1811-20. doi:10.1016/j.jacc.2017.01.052
  19. Parati G, Pengo MF, Avolio A, Azizi M, Bothe TL, Burnier M, et al. Nocturnal blood pressure: pathophysiology, measurement and clinical implications. Position paper of the European Society of Hypertension. J Hypertens. 2025;43(8):1296-318. doi:10.1097/HJH.0000000000004053
  20. Jayalath VH, de Souza RJ, Ha V, Mirrahimi A, Blanco-Mejia S, Di Buono M, et al. Sugar-sweetened beverage consumption and incident hypertension: a systematic review and meta-analysis of prospective cohorts. Am J Clin Nutr. 2015;102(4):914-21. doi:10.3945/ajcn.115.107243
  21. RIVM. Bloeddruk [internet]. Bilthoven: Volksgezondheid en Zorg (VZinfo.nl); 2026 [geraadpleegd 2 okt 2026]. Beschikbaar via: https://www.vzinfo.nl/bloeddruk
  22. RIVM. Bloeddruk - oorzaken en gevolgen [internet]. Bilthoven: Volksgezondheid en Zorg (VZinfo.nl); 2026 [geraadpleegd 2 okt 2026]. Beschikbaar via: https://www.vzinfo.nl/bloeddruk/oorzaken-en-gevolgen
  23. NHG, NIV, NVVC. Multidisciplinaire richtlijn Cardiovasculair risicomanagement (CVRM), module Bloeddrukmeting [internet]. Utrecht: Richtlijnendatabase; 2018 [beoordeeld 2021; geraadpleegd 2 okt 2026]. Beschikbaar via: https://richtlijnendatabase.nl/richtlijn/cardiovasculair_risicomanagement_cvrm/risicofactor_interventie_bij_cvrm/bloeddruk_bij_cvrm/bloeddrukmeting_bij_cvrm.html
  24. NHG, NIV, NVVC. Multidisciplinaire richtlijn Cardiovasculair risicomanagement (CVRM), module Diagnostiek bij start bloeddrukmedicatie [internet]. Utrecht: Richtlijnendatabase; 2018 [beoordeeld 2021; geraadpleegd 2 okt 2026]. Beschikbaar via: https://richtlijnendatabase.nl/richtlijn/cardiovasculair_risicomanagement_cvrm/risicofactor_interventie_bij_cvrm/bloeddruk_bij_cvrm/behandeling_bloeddruk_bij_cvrm/diagnostiek_bij_start_bloeddrukmedicatie.html
  25. NVOG. Richtlijn Hypertensieve aandoeningen in de zwangerschap, startpagina [internet]. Utrecht: Richtlijnendatabase; 2023 [geraadpleegd 2 okt 2026]. Beschikbaar via: https://richtlijnendatabase.nl/richtlijn/hypertensieve_aandoeningen_in_de_zwangerschap/startpagina_-_hypertensieve_aandoeningen_in_de_zwangerschap.html

Leververvetting

Dit werkboek is gebaseerd op 11 bronnen. Naar het werkboek

  1. European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD). J Hepatol. 2024;81(3):492-542. doi:10.1016/j.jhep.2024.04.031
  2. Younossi ZM, Koenig AB, Abdelatif D, et al. Global epidemiology of nonalcoholic fatty liver disease - meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73-84. doi:10.1002/hep.28431
  3. Vilar-Gomez E, Martinez-Perez Y, Calzadilla-Bertot L, et al. Weight loss through lifestyle modification significantly reduces features of nonalcoholic steatohepatitis. Gastroenterology. 2015;149(2):367-378.e5. doi:10.1053/j.gastro.2015.04.005
  4. Houttu V, Csader S, Nieuwdorp M, et al. Dietary interventions in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis. Front Nutr. 2021;8:716783. doi:10.3389/fnut.2021.716783
  5. Pi S, Zhang S, Zhang J, et al. Low-carbohydrate diets reduce cardiovascular risk factor levels in patients with metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of randomized controlled trials. Front Nutr. 2025;12:1626352. doi:10.3389/fnut.2025.1626352
  6. Stine JG, DiJoseph K, Pattison Z, et al. Exercise training is associated with treatment response in liver fat content by magnetic resonance imaging independent of clinically significant body weight loss in patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis. Am J Gastroenterol. 2023;118(7):1204-1213. doi:10.14309/ajg.0000000000002098
  7. Mantovani A, Petracca G, Beatrice G, et al. Non-alcoholic fatty liver disease and risk of incident diabetes mellitus: an updated meta-analysis of 501 022 adult individuals. Gut. 2021;70(5):962-969. doi:10.1136/gutjnl-2020-322572
  8. Wu S, Wu F, Ding Y, Hou J, Bi J, Zhang Z. Association of non-alcoholic fatty liver disease with major adverse cardiovascular events: a systematic review and meta-analysis. Sci Rep. 2016;6:33386. doi:10.1038/srep33386
  9. Lee D, Chiavaroli L, Ayoub-Charette S, et al. Important food sources of fructose-containing sugars and non-alcoholic fatty liver disease: a systematic review and meta-analysis of controlled trials. Nutrients. 2022;14(14):2846. doi:10.3390/nu14142846
  10. Buffey AJ, Herring MP, Langley CK, Donnelly AE, Carson BP. The acute effects of interrupting prolonged sitting time in adults with standing and light-intensity walking on biomarkers of cardiometabolic health in adults: a systematic review and meta-analysis. Sports Med. 2022;52(8):1765-1787. doi:10.1007/s40279-022-01649-4
  11. Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest. 2005;115(5):1343-1351. doi:10.1172/JCI23621

Metabool syndroom

Dit werkboek is gebaseerd op 9 bronnen. Naar het werkboek

  1. Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120(16):1640-1645. doi:10.1161/CIRCULATIONAHA.109.192644
  2. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365(9468):1415-1428. doi:10.1016/S0140-6736(05)66378-7
  3. Rohm TV, Meier DT, Olefsky JM, Donath MY. Inflammation in obesity, diabetes, and related disorders. Immunity. 2022;55(1):31-55. doi:10.1016/j.immuni.2021.12.013
  4. Sigit FS, Tahapary DL, Trompet S, et al. The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies. Diabetol Metab Syndr. 2020;12:2. doi:10.1186/s13098-019-0503-1
  5. Bos MB, de Vries JHM, Wolffenbuttel BHR, Verhagen H, Hillege JL, Feskens EJM. The prevalence of the metabolic syndrome in the Netherlands: increased risk of cardiovascular diseases and diabetes mellitus type 2 in one quarter of persons under 60. Ned Tijdschr Geneeskd. 2007;151(43):2382-2388. [in het Nederlands]
  6. Yamaoka K, Tango T. Effects of lifestyle modification on metabolic syndrome: a systematic review and meta-analysis. BMC Med. 2012;10:138. doi:10.1186/1741-7015-10-138
  7. Hu T, Mills KT, Yao L, et al. Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol. 2012;176(Suppl 7):S44-S54. doi:10.1093/aje/kws264
  8. Buxton OM, Pavlova M, Reid EW, Wang W, Simonson DC, Adler GK. Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes. 2010;59(9):2126-2133. doi:10.2337/db09-0699
  9. Buffey AJ, Herring MP, Langley CK, Donnelly AE, Carson BP. The acute effects of interrupting prolonged sitting time in adults with standing and light-intensity walking on biomarkers of cardiometabolic health in adults: a systematic review and meta-analysis. Sports Med. 2022;52(8):1765-1787. doi:10.1007/s40279-022-01649-4

Migraine

Dit werkboek is gebaseerd op 11 bronnen. Naar het werkboek

  1. Olivito I, Simona F, Tarsitano A, et al. Mediterranean ketogenic diet accounts for reduced pain frequency and intensity in patients with chronic migraine: A pilot study. Clin Nutr. 2024;43(8):1781-7. doi:10.1016/j.clnu.2024.06.015
  2. Ramsden CE, Zamora D, Faurot KR, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. doi:10.1136/bmj.n1448
  3. Caprio M, Moriconi E, Camajani E, et al. Very-low-calorie ketogenic diet vs hypocaloric balanced diet in the prevention of high-frequency episodic migraine: the EMIKETO randomized, controlled trial. J Transl Med. 2023;21(1):692. doi:10.1186/s12967-023-04561-1
  4. Neri LCL, Ferraris C, Catalano G, et al. Ketosis and migraine: a systematic review of the literature and meta-analysis. Front Nutr. 2023;10:1204700. doi:10.3389/fnut.2023.1204700
  5. Smitherman TA, Walters AB, Davis RE, et al. Randomized Controlled Pilot Trial of Behavioral Insomnia Treatment for Chronic Migraine With Comorbid Insomnia. Headache. 2016;56(2):276-91. doi:10.1111/head.12760
  6. Chang AM, Aeschbach D, Duffy JF, et al. Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness. Proc Natl Acad Sci U S A. 2015;112(4):1232-7. doi:10.1073/pnas.1418490112
  7. Nestoriuc Y, Martin A, Rief W, et al. Biofeedback treatment for headache disorders: a comprehensive efficacy review. Appl Psychophysiol Biofeedback. 2008;33(3):125-40. doi:10.1007/s10484-008-9060-3
  8. Treadwell JR, Tsou AY, Rouse B, et al. Behavioral interventions for migraine prevention: A systematic review and meta-analysis. Headache. 2025;65(4):668-94. doi:10.1111/head.14914
  9. Lemmens J, De Pauw J, Van Soom T, et al. The effect of aerobic exercise on the number of migraine days, duration and pain intensity in migraine: a systematic literature review and meta-analysis. J Headache Pain. 2019;20(1):16. doi:10.1186/s10194-019-0961-8
  10. Karsan N, Bose P, Newman J, et al. Are some patient-perceived migraine triggers simply early manifestations of the attack? J Neurol. 2021;268(5):1885-93. doi:10.1007/s00415-020-10344-1
  11. International Headache Society. ICHD-3, 8.2 Medication-overuse headache. 2018. Geraadpleegd 7 oktober 2026.

MS

Dit werkboek is gebaseerd op 10 bronnen. Naar het werkboek

  1. Lemmens CMC, Vanhommerig JW, Knottnerus BJ, et al. Prevalence and incidence of multiple sclerosis in the Netherlands. Mult Scler Relat Disord. 2025;93:106207. doi:10.1016/j.msard.2024.106207
  2. Heine M, van de Port I, Rietberg MB, van Wegen EEH, Kwakkel G. Exercise therapy for fatigue in multiple sclerosis. Cochrane Database Syst Rev. 2015;(9):CD009956. doi:10.1002/14651858.CD009956.pub2
  3. Ramanujam R, Hedström AK, Manouchehrinia A, et al. Effect of smoking cessation on multiple sclerosis prognosis. JAMA Neurol. 2015;72(10):1117-1123. doi:10.1001/jamaneurol.2015.1788
  4. Rodgers J, Friede T, Vonberg FW, et al. The impact of smoking cessation on multiple sclerosis disease progression. Brain. 2022;145(4):1368-1378. doi:10.1093/brain/awab385
  5. Veauthier C, Radbruch H, Gaede G, et al. Fatigue in multiple sclerosis is closely related to sleep disorders: a polysomnographic cross-sectional study. Mult Scler. 2011;17(5):613-622. doi:10.1177/1352458510393772
  6. Parks NE, Jackson-Tarlton CS, Vacchi L, Merdad R, Johnston BC. Dietary interventions for multiple sclerosis-related outcomes. Cochrane Database Syst Rev. 2020;(5):CD004192. doi:10.1002/14651858.CD004192.pub4
  7. Snetselaar LG, Cheek JJ, Fox SS, et al. Efficacy of diet on fatigue and quality of life in multiple sclerosis: a systematic review and network meta-analysis of randomized trials. Neurology. 2023;100(4):e357-e366. doi:10.1212/WNL.0000000000201371
  8. Mahler JV, Solti M, Apóstolos-Pereira SL, Adoni T, Silva GD, Callegaro D. Vitamin D3 as an add-on treatment for multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials. Mult Scler Relat Disord. 2024;82:105433. doi:10.1016/j.msard.2024.105433
  9. Christogianni A, O'Garro J, Bibb R, Filtness A, Filingeri D. Heat and cold sensitivity in multiple sclerosis: a patient-centred perspective on triggers, symptoms, and thermal resilience practices. Mult Scler Relat Disord. 2022;67:104075. doi:10.1016/j.msard.2022.104075
  10. Stevens CJ, Singh G, Peterson B, Vargas NT, Périard JD. The effect of cooling garments to improve physical function in people with multiple sclerosis: a systematic review and meta-analysis. Mult Scler Relat Disord. 2023;78:104912. doi:10.1016/j.msard.2023.104912

Niet-aangeboren hersenletsel

Dit werkboek is gebaseerd op 5 bronnen. Naar het werkboek

  1. Liu IH, Lin CJ, Romadlon DS, et al. Dynamic prevalence of and factors associated with fatigue following traumatic brain injury: a systematic review and meta-analysis of observational studies. J Head Trauma Rehabil. 2024;39(4):E172-E181. doi:10.1097/HTR.0000000000000904
  2. Senior HE, Leung JH, Meehan B, et al. Interventions for fatigue management after traumatic brain injury. Cochrane Database Syst Rev. 2026;(2):CD006448. doi:10.1002/14651858.CD006448.pub2
  3. Saunders DH, Sanderson M, Hayes S, et al. Physical fitness training for stroke patients. Cochrane Database Syst Rev. 2020;(3):CD003316. doi:10.1002/14651858.CD003316.pub7
  4. Hötting K, Röder B. Beneficial effects of physical exercise on neuroplasticity and cognition. Neurosci Biobehav Rev. 2013;37(9 Pt B):2243-2257. doi:10.1016/j.neubiorev.2013.04.005
  5. Thuisarts.nl. Beroerte. Nederlands Huisartsen Genootschap, Federatie Medisch Specialisten, Patiëntenfederatie Nederland. https://www.thuisarts.nl/beroerte. Geraadpleegd 20 oktober 2026.

Ontspanning

Dit werkboek is gebaseerd op 9 bronnen. Naar het werkboek

  1. Rijksinstituut voor Volksgezondheid en Milieu (RIVM). Resultaten Gezondheidsmonitor Volwassenen en Ouderen (stress, cijfers 2022). https://www.rivm.nl/resultaten-gezondheidsmonitor-volwassenen-en-ouderen. Geraadpleegd 20 oktober 2026.
  2. Rijksinstituut voor Volksgezondheid en Milieu (RIVM). Resultaten Gezondheidsmonitor Jongvolwassenen (stress, cijfers 2024). https://www.rivm.nl/resultaten-gezondheidsmonitor-jongvolwassenen. Geraadpleegd 20 oktober 2026.
  3. Fincham GW, Strauss C, Montero-Marin J, Cavanagh K. Effect of breathwork on stress and mental health: a meta-analysis of randomised-controlled trials. Sci Rep. 2023;13(1):432. doi:10.1038/s41598-022-27247-y
  4. Balban MY, Neri E, Kogon MM, et al. Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Rep Med. 2023;4(1):100895. doi:10.1016/j.xcrm.2022.100895
  5. Hackett RA, Steptoe A. Type 2 diabetes mellitus and psychological stress - a modifiable risk factor. Nat Rev Endocrinol. 2017;13(9):547-560. doi:10.1038/nrendo.2017.64
  6. Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: a meta-analysis of randomised controlled trials. Sleep Med Rev. 2021;60:101556. doi:10.1016/j.smrv.2021.101556
  7. Ebrahim IO, Shapiro CM, Williams AJ, Fenwick PB. Alcohol and sleep I: effects on normal sleep. Alcohol Clin Exp Res. 2013;37(4):539-549. doi:10.1111/acer.12006
  8. Singh B, Olds T, Curtis R, et al. Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews. Br J Sports Med. 2023;57(18):1203-1209. doi:10.1136/bjsports-2022-106195
  9. Thuisarts.nl. Ik ben overspannen. Nederlands Huisartsen Genootschap, Federatie Medisch Specialisten, Patiëntenfederatie Nederland. https://www.thuisarts.nl/overspannen/ik-ben-overspannen. Laatst gewijzigd 15 oktober 2025. Geraadpleegd 20 oktober 2026.

Osteoporose

Dit werkboek is gebaseerd op 9 bronnen. Naar het werkboek

  1. Sherrington C, Fairhall NJ, Wallbank GK, et al. Exercise for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2019;1(1):CD012424. doi:10.1002/14651858.CD012424.pub2
  2. Brooke-Wavell K, Skelton DA, Barker KL, et al. Strong, steady and straight: UK consensus statement on physical activity and exercise for osteoporosis. Br J Sports Med. 2022;56(15):837-46. doi:10.1136/bjsports-2021-104634
  3. Seppala LJ, Wermelink AMAT, de Vries M, et al. Fall-Risk-Increasing Drugs: A Systematic Review and Meta-Analysis: II. Psychotropics. J Am Med Dir Assoc. 2018;19(4):371.e11-371.e17. doi:10.1016/j.jamda.2017.12.098
  4. Bauer J, Biolo G, Cederholm T, et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc. 2013;14(8):542-59. doi:10.1016/j.jamda.2013.05.021
  5. Zhao JG, Zeng XT, Wang J, et al. Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis. JAMA. 2017;318(24):2466-82. doi:10.1001/jama.2017.19344
  6. Malmir H, Saneei P, Larijani B, et al. Adherence to Mediterranean diet in relation to bone mineral density and risk of fracture: a systematic review and meta-analysis of observational studies. Eur J Nutr. 2018;57(6):2147-60. doi:10.1007/s00394-017-1490-3
  7. De Laet C, Kanis JA, Odén A, et al. Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int. 2005;16(11):1330-8. doi:10.1007/s00198-005-1863-y
  8. Cummings SR, Ferrari S, Eastell R, et al. Vertebral Fractures After Discontinuation of Denosumab: A Post Hoc Analysis of the Randomized Placebo-Controlled FREEDOM Trial and Its Extension. J Bone Miner Res. 2018;33(2):190-8. doi:10.1002/jbmr.3337
  9. National Osteoporosis Guideline Group. NOGG 2024 Clinical guideline. Section 5: Non-pharmacological management of osteoporosis. Geraadpleegd 7 oktober 2026.

Parkinson

Dit werkboek is gebaseerd op 6 bronnen. Naar het werkboek

  1. Trinh J, de Vries NM, Chan P, et al. The role of lifestyle interventions in symptom management and disease modification in Parkinson's disease. Lancet Neurol. 2026;25(1):90-102. doi:10.1016/S1474-4422(25)00305-9
  2. Ernst M, Folkerts AK, Gollan R, et al. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024;4(4):CD013856. doi:10.1002/14651858.CD013856.pub3
  3. Boelens Keun JT, Arnoldussen IA, Vriend C, et al. Dietary approaches to improve efficacy and control side effects of levodopa therapy in Parkinson's disease: a systematic review. Adv Nutr. 2021;12(6):2265-2287. doi:10.1093/advances/nmab060
  4. van der Heide A, Speckens AEM, Meinders MJ, et al. Stress and mindfulness in Parkinson's disease - a survey in 5000 patients. NPJ Parkinsons Dis. 2021;7(1):7. doi:10.1038/s41531-020-00152-9
  5. Schapira AHV, Chaudhuri KR, Jenner P. Non-motor features of Parkinson disease. Nat Rev Neurosci. 2017;18(7):435-450. doi:10.1038/nrn.2017.62
  6. Grammatikopoulou MG, Tousinas G, Balodimou C, et al. Ketogenic therapy for Parkinson's disease: a systematic review and synthesis without meta-analysis of animal and human trials. Maturitas. 2022;163:46-61. doi:10.1016/j.maturitas.2022.06.001

Reflux

Dit werkboek is gebaseerd op 8 bronnen. Naar het werkboek

  1. Ong AM, Chua LT, Khor CJ, et al. Diaphragmatic Breathing Reduces Belching and Proton Pump Inhibitor Refractory Gastroesophageal Reflux Symptoms. Clin Gastroenterol Hepatol. 2018;16(3):407-416.e2. doi:10.1016/j.cgh.2017.10.038
  2. Albarqouni L, Moynihan R, Clark J, et al. Head of bed elevation to relieve gastroesophageal reflux symptoms: a systematic review. BMC Fam Pract. 2021;22(1):24. doi:10.1186/s12875-021-01369-0
  3. Schuitenmaker JM, Kuipers T, Oude Nijhuis RAB, et al. Sleep Positional Therapy for Nocturnal Gastroesophageal Reflux: A Double-Blind, Randomized, Sham-Controlled Trial. Clin Gastroenterol Hepatol. 2022;20(12):2753-2762.e2. doi:10.1016/j.cgh.2022.02.058
  4. Gu C, Olszewski T, King KL, et al. The Effects of Modifying Amount and Type of Dietary Carbohydrate on Esophageal Acid Exposure Time and Esophageal Reflux Symptoms: A Randomized Controlled Trial. Am J Gastroenterol. 2022;117(10):1655-67. doi:10.14309/ajg.0000000000001889
  5. Mone I, Kraja B, Bregu A, et al. Adherence to a predominantly Mediterranean diet decreases the risk of gastroesophageal reflux disease: a cross-sectional study in a South Eastern European population. Dis Esophagus. 2016;29(7):794-800. doi:10.1111/dote.12384
  6. Lakananurak N, Pitisuttithum P, Susantitaphong P, et al. The Efficacy of Dietary Interventions in Patients with Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Intervention Studies. Nutrients. 2024;16(3). doi:10.3390/nu16030464
  7. Calvo LLJ, García Cámara P, Llorente Barrio M, et al. Successful deprescribing of proton pump inhibitors with a patient-centered process: the DESPIBP Project. Eur J Clin Pharmacol. 2021;77(12):1927-33. doi:10.1007/s00228-021-03186-x
  8. Katz PO, Dunbar KB, Schnoll-Sussman FH, et al. ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease. Am J Gastroenterol. 2022;117:27-56. doi:10.14309/ajg.0000000000001538

Reuma

Dit werkboek is gebaseerd op 9 bronnen. Naar het werkboek

  1. RIVM. Reumatoïde artritis (RA). Volksgezondheid en Zorg. Cijfers 2024; geraadpleegd 7 oktober 2026.
  2. Wagenaar CA, Walrabenstein W, van der Leeden M, et al. Long-term effectiveness of a lifestyle intervention for rheumatoid arthritis and osteoarthritis: 1-year follow-up of the 'Plants for Joints' randomised clinical trial. RMD Open. 2024;10(1). doi:10.1136/rmdopen-2023-004025
  3. Rausch Osthoff AK, Niedermann K, Braun J, et al. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. Ann Rheum Dis. 2018;77(9):1251-60. doi:10.1136/annrheumdis-2018-213585
  4. Philippou E, Petersson SD, Rodomar C, et al. Rheumatoid arthritis and dietary interventions: systematic review of clinical trials. Nutr Rev. 2021;79(4):410-28. doi:10.1093/nutrit/nuaa033
  5. Klaasen R, Wijbrandts CA, Gerlag DM, et al. Body mass index and clinical response to infliximab in rheumatoid arthritis. Arthritis Rheum. 2011;63(2):359-64. doi:10.1002/art.30136
  6. Tang NK, Lereya ST, Boulton H, et al. Nonpharmacological Treatments of Insomnia for Long-Term Painful Conditions: A Systematic Review and Meta-analysis of Patient-Reported Outcomes in Randomized Controlled Trials. Sleep. 2015;38(11):1751-64. doi:10.5665/sleep.5158
  7. Saevarsdottir S, Wedrén S, Seddighzadeh M, et al. Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Register cohorts. Arthritis Rheum. 2011;63(1):26-36. doi:10.1002/art.27758
  8. Smolen JS, Landewé RBM, Bergstra SA, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update. Ann Rheum Dis. 2023;82(1):3-18. doi:10.1136/ard-2022-223356
  9. Gwinnutt JM, Wieczorek M, Balanescu A, et al. 2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases. Ann Rheum Dis. 2023;82(1):48-56. doi:10.1136/annrheumdis-2021-222020

Rugklachten

Dit werkboek is gebaseerd op 8 bronnen. Naar het werkboek

  1. Haddadj R, Nordstoga AL, Nilsen TIL, et al. Volume and Intensity of Walking and Risk of Chronic Low Back Pain. JAMA Netw Open. 2025;8(6):e2515592. doi:10.1001/jamanetworkopen.2025.15592
  2. Hayden JA, Ellis J, Ogilvie R, et al. Exercise therapy for chronic low back pain. Cochrane Database Syst Rev. 2021;9(9):CD009790. doi:10.1002/14651858.CD009790.pub2
  3. Ho EK, Chen L, Simic M, et al. Psychological interventions for chronic, non-specific low back pain: systematic review with network meta-analysis. BMJ. 2022;376:e067718. doi:10.1136/bmj-2021-067718
  4. Chen LH, Weber K, Mehrabkhani S, et al. The effectiveness of weight loss programs for low back pain: a systematic review. BMC Musculoskelet Disord. 2022;23(1):488. doi:10.1186/s12891-022-05391-w
  5. Kawabata S, Kurita N, Nikaido T, et al. Association between lifestyle-related factors and low back pain: Evidence from a Japanese population-based study. PLoS One. 2025;20(7):e0328684. doi:10.1371/journal.pone.0328684
  6. Kovacs FM, Abraira V, Peña A, et al. Effect of firmness of mattress on chronic non-specific low-back pain: randomised, double-blind, controlled, multicentre trial. Lancet. 2003;362(9396):1599-604. doi:10.1016/S0140-6736(03)14792-7
  7. Tataryn N, Simas V, Catterall T, et al. Posterior-Chain Resistance Training Compared to General Exercise and Walking Programmes for the Treatment of Chronic Low Back Pain in the General Population: A Systematic Review and Meta-Analysis. Sports Med Open. 2021;7(1):17. doi:10.1186/s40798-021-00306-w
  8. Dahm KT, Brurberg KG, Jamtvedt G, et al. Advice to rest in bed versus advice to stay active for acute low-back pain and sciatica. Cochrane Database Syst Rev. 2010;2010(6):CD007612. doi:10.1002/14651858.CD007612.pub2

Slaap

Dit werkboek is gebaseerd op 6 bronnen. Naar het werkboek

  1. Hirshkowitz M, Whiton K, Albert SM, et al. National Sleep Foundation's updated sleep duration recommendations: final report. Sleep Health. 2015;1(4):233-243. doi:10.1016/j.sleh.2015.10.004
  2. Buxton OM, Pavlova M, Reid EW, et al. Sleep restriction for 1 week reduces insulin sensitivity in healthy men. Diabetes. 2010;59(9):2126-2133. doi:10.2337/db09-0699
  3. Reutrakul S, Van Cauter E. Sleep influences on obesity, insulin resistance, and risk of type 2 diabetes. Metabolism. 2018;84:56-66. doi:10.1016/j.metabol.2018.02.010
  4. Taheri S, Lin L, Austin D, et al. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1(3):e62. doi:10.1371/journal.pmed.0010062
  5. Drake C, Roehrs T, Shambroom J, et al. Caffeine effects on sleep taken 0, 3, or 6 hours before going to bed. J Clin Sleep Med. 2013;9(11):1195-1200. doi:10.5664/jcsm.3170
  6. Kredlow MA, Capozzoli MC, Hearon BA, et al. The effects of physical activity on sleep: a meta-analytic review. J Behav Med. 2015;38(3):427-449. doi:10.1007/s10865-015-9617-6

Stoppen met roken

Dit werkboek is gebaseerd op 7 bronnen. Naar het werkboek

  1. World Health Organization. Tobacco: health benefits of smoking cessation [Internet]. Geneva: World Health Organization; 2020 [geraadpleegd 2026 okt 20]. Beschikbaar via: https://www.who.int/news-room/questions-and-answers/item/tobacco-health-benefits-of-smoking-cessation.
  2. Hartmann-Boyce J, Livingstone-Banks J, Ordóñez-Mena JM, et al. Behavioural interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst Rev. 2021;1(1):CD013229. doi:10.1002/14651858.CD013229.pub2
  3. Stead LF, Carroll AJ, Lancaster T. Group behaviour therapy programmes for smoking cessation. Cochrane Database Syst Rev. 2017;3(3):CD001007. doi:10.1002/14651858.CD001007.pub3
  4. Hartmann-Boyce J, Chepkin SC, Ye W, et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018;5(5):CD000146. doi:10.1002/14651858.CD000146.pub5
  5. Lindson-Hawley N, Banting M, West R, et al. Gradual versus abrupt smoking cessation: a randomized, controlled noninferiority trial. Ann Intern Med. 2016;164(9):585-592. doi:10.7326/M14-2805
  6. Lindson N, Livingstone-Banks J, Butler AR, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. 2026;8(8):CD010216. doi:10.1002/14651858.CD010216.pub11
  7. Aveyard P, Lindson N, Tearne S, et al. Nicotine preloading for smoking cessation: the Preloading RCT. Health Technol Assess. 2018;22(41):1-84. doi:10.3310/hta22410

Verbinding

Dit werkboek is gebaseerd op 4 bronnen. Naar het werkboek

  1. Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med. 2010;7(7):e1000316. doi:10.1371/journal.pmed.1000316
  2. Wang F, Gao Y, Han Z, et al. A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality. Nat Hum Behav. 2023;7(8):1307-1319. doi:10.1038/s41562-023-01617-6
  3. Gordon-Hecker T, Choshen-Hillel S, Ben-Simon E, et al. Restless nights, cold hearts: poor sleep causally blunts empathy. Int J Clin Health Psychol. 2025;25(1):100548. doi:10.1016/j.ijchp.2025.100548
  4. Middleton G, Patterson KA, Muir-Cochrane E, et al. The health and well-being impacts of community shared meal programs for older populations: a scoping review. Innov Aging. 2022;6(7):igac068. doi:10.1093/geroni/igac068

Voeding

Dit werkboek is gebaseerd op 3 bronnen. Naar het werkboek

  1. Vellinga RE, van Bakel M, Biesbroek S, et al. Evaluation of foods, drinks and diets in the Netherlands according to the degree of processing for nutritional quality, environmental impact and food costs. BMC Public Health. 2022;22(1):877. doi:10.1186/s12889-022-13282-x
  2. Lane MM, Gamage E, Du S, et al. Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses. BMJ. 2024;384:e077310. doi:10.1136/bmj-2023-077310
  3. Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. N Engl J Med. 2018;378(25):e34. doi:10.1056/NEJMoa1800389

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